Graft versus Host Disease (GvHD)

Graft versus host disease (GvHD) is a condition that might occur after a transplant. The donated bone marrow in the case of GvHD, or peripheral blood stem cells view the recipient’s body as foreign, and the donated cells/bone marrow attack the body.

Forms of GvHD

• Acute graft versus host disease (Acute GvHD).
• icon Chronic graft versus host disease (Chronic GvHD).

As a transplant recipient, you might experience either form of GvHD, both forms.

Acute GvHD occurs when the donor’s cells are being engrafted in the transplant recipient. It might develop in your eyes, liver, skin gastrointestinal tract, and these symptoms might appear within weeks.

Chronic GvHD can appear at any time after allogeneic transplants or several years after your transplant. Chronic GvHD might occur in the mouth, eyes, skin, lungs, liver, gastrointestinal tract, genitourinary tract, or neuromuscular system.

Symptoms to report

Symptoms of Acute GvHD might include any of the following:

•  Skin rash or reddened areas on the skin (signs of Acute GvHD of the skin).
•  Yellow discoloration of the eyes and/or skin, and abnormal blood test.
•  Nausea, vomiting, diarrhea, or abdominal cramping (signs of Acute GvHD in the gastrointestinal tract, or “gut”).
•  Increased irritation of the eyes.

Symptoms of Chronic GvHD might include any of the following:

• Skin thickening or tightening, Rash, raised, or discolored areas.
• Yellow discoloration of the skin and/or eyes, abdominal swelling, and abnormal blood test results.
• Dry eyes or vision changes.
• Pain or sensitivity to spicy foods, Dry mouth, white patches inside the mouth.
• Shortness of breath or changes are seen on the chest X-ray.
• Pain or difficulty with swallowing, or weight loss.
• Fatigue, muscle weakness, or pain.

How Stem Cells Treatment May Help:

A promising treatment option for Acute GvHD consists of an infusion of bone marrow donor Mesenchymal Stromal Cells(MSC). MSCs have been used in the treatment of Acute GvHD due to their inhibitory effects on the proliferation and cytotoxic activity of immune system cells.

Prasad Hospitals cultures clinical-grade best stem cell therapy for disorders in India. We have the expertise of working with the best hematologists in providing the MSCs for GvHD.

What Sets Us Apart:

• Best Hospital for Stem Cell Therapy For Disorders in Hyderabad.
• Board with the best hematologists, clinicians, and doctors overlooking the process.
• Ethics committee board overlooking the process from an ethics perspective.
• India’s best research and practice-oriented stem-cell research practice.