Prasad Hospitals >> Sickle Cell Anaemia
Sickle cell anemia is to be an inborn error leading to the blood disorder, affecting many people in India. It is passed over to the child through affected or carrier parents. Studies indicate that, if both the parents have contributed one affected gene to the child, there can be a possibility of synthesizing abnormal or sickle hemoglobin by the body.
Although there is no widely accepted treatment for sickle cell disease. A few children with the disease have been effectively treated using blood stem cells or bone marrow, transplants. Until recently, bone marrow transplants were perceived to be highly toxic for adults with sickle cell anemia. A procedure in which, chemotherapy is used to kill a patient’s marrow before being replaced with that belonging to a donor.
The blood of a newborn’s umbilical cord is a rich source of hematopoietic stem cells for transplantation. Because the donor newborn’s immune system is still immature, the stem cells are less likely to induce an adverse immune reaction in the receiver, If the transplant is successful, the sickle cell patient may well be cured.